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相关基因
HIF1A
位点：RS11549465
NAT2
位点：RS1208
AMPD1
位点：RS17602729
ADRB3
位点：RS4994
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Torres O, et al. Lack of association between hypoxia inducible factor-1 alpha gene polymorphisms and biopsy-proven giant cell arteritis. 2010
Knechtel G, et al. Single nucleotide polymorphisms in the hypoxia-inducible factor-1 gene and colorectal cancer risk. 2010
Ruiz-Tovar J, et al. Association of thymidylate synthase and hypoxia inducible factor-1alpha DNA polymorphisms with pancreatic cancer. 2012
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Heino S, et al. Non-synonymous sequence variants within the oxygen-dependent degradation domain of the HIF1A gene are not associated with pre-eclampsia in the Finnish population. 2008
Droma Y, et al. Two hypoxia sensor genes and their association with symptoms of acute mountain sickness in Sherpas. 2008
Wipff J, et al. Association of hypoxia-inducible factor 1A (HIF1A) gene polymorphisms with systemic sclerosis in a French European Caucasian population. 2015
Konac E, et al. Genetic variations in the hypoxia-inducible factor-1alpha gene and lung cancer. 2009
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Eynon N, et al. Is the interaction between HIF1A P582S and ACTN3 R577X determinant for power/sprint performance? 2010
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Xu CF, et al. Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism. 2010
Kim SJ, et al. The association of 18F-deoxyglucose (FDG) uptake of PET with polymorphisms in the glucose transporter gene (SLC2A1) and hypoxia-related genes (HIF1A, VEGFA, APEX1) in non-small cell lung cancer. SLC2A1 polymorphisms and FDG-PET in NSCLC patients. 2010
Qin C, et al. The polymorphisms in the VHL and HIF1A genes are associated with the prognosis but not the development of renal cell carcinoma. 2012
Gerger A, et al. Pharmacogenetic angiogenesis profiling for first-line Bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer. 2011
Li P, et al. Genetic polymorphisms in HIF1A are associated with prostate cancer risk in a Chinese population. 2012
Bravatà V, et al. Genotyping analysis and ¹⁸FDG uptake in breast cancer patients: a preliminary research. 2013
Fu SL, et al. A polymorphism in the 3' untranslated region of Hypoxia-Inducible Factor-1 alpha confers an increased risk of cervical cancer in a Chinese population. 2013
Fraga A, et al. The HIF1A functional genetic polymorphism at locus +1772 associates with progression to metastatic prostate cancer and refractoriness to hormonal castration. 2014
Fu SL, et al. A polymorphism in the 3' untranslated region of Hypoxia-Inducible Factor-1 alpha confers an increased risk of cervical cancer in a Chinese population. 2015
Feng CC, et al. Lack of association between the polymorphisms of hypoxia-inducible factor 1A (HIF1A) gene and SLE susceptibility in a Chinese population. 2014
Liu J, et al. 1790 G/A polymorphism, but not 1772 C/T polymorphism, is significantly associated with cancers: an update study. 1772
Mikuls TR, et al. Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans. 2012
Hein DW, et al. Accuracy of various human NAT2 SNP genotyping panels to infer rapid, intermediate and slow acetylator phenotypes. 2012
Buxens A, et al. Can we predict top-level sports performance in power vs endurance events? A genetic approach. 2011
Crabtree MD, et al. Analysis of candidate modifier loci for the severity of colonic familial adenomatous polyposis, with evidence for the importance of the N-acetyl transferases. 2004
García-Closas M, et al. NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses. 2005
Patin E, et al. Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes. 2006
Morton LM, et al. Genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2) and risk of non-Hodgkin lymphoma. 2006
Dai Z, et al. Genotyping panel for assessing response to cancer chemotherapy. 2008
Agúndez JA, et al. Unraveling ambiguous NAT2 genotyping data. 2008
Walraven JM, et al. Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2. 2008
Luca F, et al. Multiple advantageous amino acid variants in the NAT2 gene in human populations. 2008
Chang MH, et al. Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994. 2009
Sabbagh A, et al. Evaluating NAT2PRED for inferring the individual acetylation status from unphased genotype data. 2009
Vatsis KP, et al. Diverse point mutations in the human gene for polymorphic N-acetyltransferase. 1991
Grant DM, et al. A simple test for acetylator phenotype using caffeine. 1984
Cascorbi I, et al. NAT2*12A (803A-->G) codes for rapid arylamine n-acetylation in humans. 1996
Gil J, et al. CYP1A1 Ile462Val polymorphism and colorectal cancer risk in Polish patients. 2014
Genetta T, et al. A novel bipartite intronic splicing enhancer promotes the inclusion of a mini-exon in the AMP deaminase 1 gene. 2001
Lucia A, et al. C34T mutation of the AMPD1 gene in an elite white runner. 2006
Anderson JL, et al. A common variant of the AMPD1 gene predicts improved cardiovascular survival in patients with coronary artery disease. 2000
Ramakers BP, et al. Circulating adenosine increases during human experimental endotoxemia but blockade of its receptor does not influence the immune response and subsequent organ injury. 2011
Yamaguchi-Kabata Y, et al. Distribution and effects of nonsense polymorphisms in human genes. 2008
Won HH, et al. Cataloging coding sequence variations in human genome databases. 2008
Ruiz JR, et al. Is there an optimum endurance polygenic profile? 2009
Eynon N, et al. Genes for elite power and sprint performance: ACTN3 leads the way. 2013
Hennis PJ, et al. Genetic factors associated with exercise performance in atmospheric hypoxia. 2015
Pacanowski MA, et al. Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women's Ischemia Syndrome Evaluation. 2008
Santiago C, et al. Trp64Arg polymorphism in ADRB3 gene is associated with elite endurance performance. 2011
Vargas-Alarcón G, et al. Association of adrenergic receptor gene polymorphisms with different fibromyalgia syndrome domains. 2009
Cruz M, et al. Candidate gene association study conditioning on individual ancestry in patients with type 2 diabetes and metabolic syndrome from Mexico City. 2010
Wang B, et al. Positive correlation between Beta-3-Adrenergic Receptor (ADRB3) gene and gout in a Chinese male population. 2011
Takeuchi S, et al. ADRB3 polymorphism associated with BMI gain in Japanese men. 2012
Lima JJ, et al. Association analyses of adrenergic receptor polymorphisms with obesity and metabolic alterations. 2007
Nemoto M, et al. Genetic association of glutathione peroxidase-1 with coronary artery calcification in type 2 diabetes: a case control study with multi-slice computed tomography. 2007
Haworth CM, et al. No evidence for association between BMI and 10 candidate genes at ages 4, 7 and 10 in a large UK sample of twins. 2008
Marvelle AF, et al. Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort. 2008
Penco S, et al. New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background. 2008
Simoni M, et al. Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response. 2008
Feigelson HS, et al. Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II. 2008
Chang MH, et al. Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994. 2009
Wang X, et al. A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. 2009
Zee RY, et al. Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach. 2009
Abhary S, et al. A systematic meta-analysis of genetic association studies for diabetic retinopathy. 2009
Gómez-Gallego F, et al. Are elite endurance athletes genetically predisposed to lower disease risk? 2010
Fan AZ, et al. Gene polymorphisms in association with emerging cardiovascular risk markers in adult women. 2010
Jing C, et al. Meta-analysis of association studies between five candidate genes and type 2 diabetes in Chinese Han population. 2012
Likanonsakul S, et al. Polymorphisms in Fas gene is associated with HIV-related lipoatrophy in Thai patients. 2013
Kumar S, et al. Significant role of ADRB3 rs4994 towards the development of coronary artery disease. 2014
Sasaki M, et al. Angiotensinogen gene polymorphisms and food-intake behavior in young, normal female subjects in Japan. 2013
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