费力科思 费力科思 - WeGene勤杂工 母系单倍群

JAMA子刊新报道:线粒体单倍群 I, J, K, O-X, T, U , A和M的自闭症风险较高

JAMA Psychiatry的8月23日发表的研究成果:Of 1624 patients with autism included in this study, 1299 were boys (80%) and 325 were girls (20%). Families in the Autism Genetic Resource Exchange collection (933 families, encompassing 4041 individuals: 1624 patients with ASD and 2417 healthy parents and siblings) had been previously recruited in the United States with no restrictions on age, sex, race/ethnicity, or socioeconomic status. Relative to the most common European haplogroup HHV, European haplogroups I, J, K, O-X, T, and U were associated with increased risk of ASD, as were Asian and Native American haplogroups A and M, with odds ratios ranging from 1.55 (95% CI, 1.16-2.06) to 2.18 (95% CI, 1.59-3) (adjusted P < .04). Hence, mtDNA haplogroup variation is an important risk factor for ASD.
 
参考文献:http://jamanetwork.com/journals/jamapsychiatry/article-abstract/2649278
 
母系是B的表示没有压力啊
2017-08-27 • IP属地广州
按热门排序    按默认排序

6 个回复

费力科思 - WeGene勤杂工
就没有这几个线粒体单倍群的人么。。。
意思是母系祖源开头字母是这些吗?我的是A
努力的KCNQ1基因 [禁言中]
[ 由于内容不当, 此内容已被隐藏 ]
费力科思 - WeGene勤杂工
1503835784565.jpg


这个N9a的糖尿病在case组和control组的区别只是3%和5%的区别啊
 
按发病率算,确实快翻倍了
除了M,其他的都没见过
AMD_Yes - Freedom is not free!
本人U已中招了!

要回复问题请先登录注册