wang wang - 哈佛医学院、德国马普所分子人类学博士后 祖源分析

Nature:东亚人群也有至少5-10%的西欧亚成分?

David Reich实验室昨天新发nature论文解析最早的农民:Genomic insights into the origin of farming in the ancient Near East
We report genome-wide ancient DNA from 44 ancient Near Easterners ranging in time between ~12,000 and 1,400 BCE, from Natufian hunter–gatherers to Bronze Age farmers. We show that the earliest populations of the Near East derived around half their ancestry from a ‘Basal Eurasian’ lineage that had little if any Neanderthal admixture and that separated from other non-African lineages before their separation from each other. The first farmers of the southern Levant (Israel and Jordan) and Zagros Mountains (Iran) were strongly genetically differentiated, and each descended from local hunter–gatherers. By the time of the Bronze Age, these two populations and Anatolian-related farmers had mixed with each other and with the hunter–gatherers of Europe to drastically reduce genetic differentiation. The impact of the Near Eastern farmers extended beyond the Near East: farmers related to those of Anatolia spread westward into Europe; farmers related to those of the Levant spread southward into East Africa; farmers related to those from Iran spread northward into the Eurasian steppe; and people related to both the early farmers of Iran and to the pastoralists of the Eurasian steppe spread eastward into South Asia.
 
爆点在于最后一部分模拟东亚人群里的西欧亚成分:no less than ~5–10% ANE in diverse East Asian groups including Han Chinese,这里的ANE指的是西伯利亚的Mal'ta1,这直接颠覆了我们对史前人群混合的理解,但所用方法、所做假设是否正确就还需要后续验证。
 
 
 
2016-07-26 • IP属地德国
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10 个回复

黄隆思 - 红领巾三段
阅。
cedre - -----------------------------------------------------------
Society for Molecular Biology and Evolution Conference 2016的会议论文,
The Neolithic in Northeast Asia in light of a 7,700 year-old genome   
俄朝边境的2例古dna,应该是通古斯人的直系祖先了“These hunter-gatherers are genetically most similar to geographically close populations from the Amur Basin, in particular the Ulchi, implying a high level of continuity in this region over most of the Holocene.”
没有全文,应该还没有正式发表在期刊上,不知能否提前看到。。。
这个数据应该可以解决韩国祖源的问题。。。
 
http://smbe-2016.p.asnevents.com.au/days/2016-07-04/abstract/34323
cedre - -----------------------------------------------------------
The preliminary report for the deep sequencing of the prehistoric Jomon genome from the Japanese archipelago - Hiroki OOTA
绳纹人的也有了。。。
shuer - 一句话介绍
都是外文看不懂,谁能翻译一下就好了
应该有, 人类好像是在中亚分成东亚人种和白种人。但还有一支从南方进入中国, 他们可能是百越的祖先吧。
我比一般的中国人更东南亚 / 西域吗?

本人籍贯3/4重庆, 1/4西北。基本上还是算南方人。

Wegene:
南方汉族 49.37
北方汉族 37.94
藏缅族群 8.21
高山族群 0.71
其他 0.02
东北亚
日本 3.50
其他 0%

其他 0.03


K7b:
East Asian-83.87
Siberian-14.93
South Asian-0.46
Atlantic-Baltic-0.37
West Asian-0.24
Southern-0.12
西域1.20


Geno 2.0
Northeast Asian-56%
Southeast Asia and Oceania-44%

他们中国人的标准样本东北亚比我多, 而且还有我缺少的中亚和西伯利亚成分。


Family Tree DNA 55% 东北亚 45% 东南亚


23andMe 忘了, 但大概是

99.5% 东亚和北美原住民
96.9% Chinese
0.5% Korean
0.6% Southeast Asian
1.4% Broadly East Asian
0.1% Broadly East Asian and Native American

0.3% European
0.1% 东欧
0.1% 南欧
0.1% 泛欧洲

0.1% 南亚

不到0.1% 中非和南非


湿耳候
喝酒不脸红
头发5个SNP里3个直发, 2个卷发
10% Blonde
O2a2b, M7b1a1b
Lipson 和 Reich 又发表了一篇文章。这次的计算结果里 Mal'ta1 有一些古东部欧亚成分。
东欧亚人群里确实应该有一定的西欧亚成分,但把整个ANE都算作西欧亚可能并不合适。ANE的全称是Ancient North Eurasia,这一成分相关人群可能生活在中亚到西伯利亚的广大地区。
我之前在微解读发起过一个和西欧亚浅肤色突变SLC24A5相关的调查,发现具有西欧亚突变类型的比例并不算少。我统计的基因频率是9.26%,但考虑到是有明显性状表现的基因,统计的样本可能会有偏差,因为浅肤色测这个位点人可能会更多。
恰好在最开始的时候该位点已经有人发起过解读,虽然当时称之为“保持虾头不黑”之类很奇怪的名字,但却可以保证数据样本不具备偏向性。根据那份样本得出的基因频率是6.6%,我认为这应该能够代表该突变在东亚地区的一个平均水平。
鉴于该突变出现的时间可能相对较晚(不早于2万年),可以提供一个参考。东亚人的西欧亚、中亚成分,主要是来自中亚的ANE成分很可能大都是在两万年末次盛冰期结束后融入的,而且很可能是来自于历史时期的东西方交流。这一点可以在未来通过不同时期的古DNA进行验证。
微基因或gedmatch 里哪一项是西欧亚

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